Renal impairment Pregabalin is eliminated from the systemic circulation largely by renal excretion as unchanged drug. As pregabalin clearance is specifically proportional to creatinine clearance (see section 5. The dosage could possibly be adjusted throughout the 1st week (to 150mg 2 times every day) if deemed acceptable by a physician. https://peterf542tfo4.thenerdsblog.com/profile