This mechanism, called presynaptic inhibition, happens when a postsynaptic neuron releases endocannabinoids in retrograde transmission, which then bind to cannabinoid receptors to the presynaptic terminal. CB1 receptors then decrease the quantity of neurotransmitter introduced, to make sure that subsequent excitation within the presynaptic neuron brings about diminished effects within... https://israelrmamw.59bloggers.com/33452767/endocannabinoid-system-secrets