There exists a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors within the dorsal horn to minimize afferent soreness transmission and deliver analgesia. As a result, medicine like clonidine that goal alpha-two receptors can impact the transmission of pain. Applies to clonidine: oral tablet, https://alfredy061ulb7.techionblog.com/profile